buy oxycontin 80mg Australia

buy OxyContin  Australia buy oxycontin https://buyketamina.com/wp-admin/post-new.php?post_type=productAustralia sold under various brand names such as Roxicodone and OxyContin (which is the extended release form), is a strong, semi-synthetic opioid used medically for treatment of moderate to severe pain. It is highly addictive^[12] and a commonly abused drug.^[13][14] It is usually taken by mouth, and is available in immediate-release and controlled-release formulations.^[13] Onset of pain relief typically begins within fifteen minutes and lasts for up to six hours with the immediate-release formulation.^[13] In the United Kingdom, it is available by injection.^[15] Combination products are also available with paracetamol (acetaminophen), ibuprofen, naloxone, naltrexone, and aspirin.^[13]

Common side effects include euphoria, constipation, nausea, vomiting, loss of

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appetite, drowsiness, dizziness, itching, dry mouth, and sweating.^[13] Severe side effects may include addiction and dependence, substance abuse, irritability, depression or mania, delirium, hallucinations, hypoventilation, gastroparesis, bradycardia, and hypotension.^[13] Those allergic to codeine may also be allergic to oxycodone.^[13] Use of oxycodone in early pregnancy appears relatively safe.^[13] Opioid withdrawal may occur if rapidly stopped.^[13] Oxycodone acts by activating the μ-opioid receptor.^[16] When taken by mouth, it has roughly 1.5 times the effect of the equivalent amount of morphine.^[17]

Oxycodone was first made in Germany in 1916 from thebaine.^[18] It is on the World Health Organization’s List of Essential Medicines.^[19] It is available as a generic medication.^[13] In 2020, it was the 54th most commonly prescribed medication in the United States, with more than 12 million prescriptions.^[20][21] A number of abuse-deterrent formulations are available, such as in combination with naloxone or naltrexone.^[14][22]

Oxycodone is used for managing moderate to severe acute or chronic pain when other treatments are not sufficient.^[13] It may improve quality of life in certain types of pain.^[23] It is unclear if use in chronic pain results in improved quality of life or ongoing pain relief.^[13]